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  Indian J Med Microbiol
 

Figure 1: (a) The DNA sequence of C*03:187 is identical to C*03:03:01:01 from exon 1 to 7, except for codon 152 of exon 3 (shown here), where GAG (underlined)of C*03:03:01:01 is substituted by GTG (underlined) in C*03:187. (b) The nucleotide substitution introduces one amino acid replacement at the residue 152 where glutamic acid (E) (shaded) of C*03:03:01:01 is replaced by a valine (V) (shaded) in C*03:187. Dashes indicate nucleotide or amino acid identity with C*03:03:01:01

Figure 1: (a) The DNA sequence of C*03:187 is identical to C*03:03:01:01 from exon 1 to 7, except for codon 152 of exon 3 (shown here), where GAG (underlined)of C*03:03:01:01 is substituted by GTG (underlined) in C*03:187. (b) The nucleotide substitution introduces one amino acid replacement at the residue 152 where glutamic acid (E) (shaded) of C*03:03:01:01 is replaced by a valine (V) (shaded) in C*03:187. Dashes indicate nucleotide or amino acid identity with C*03:03:01:01