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 Table of Contents  
LETTER TO THE EDITOR
Year : 2017  |  Volume : 29  |  Issue : 4  |  Page : 237

Leptin as an independent marker of metabolic syndrome


1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Tropical Medicine, Hainan Medical University, Hainan Sheng, China

Date of Web Publication4-Dec-2017

Correspondence Address:
Beuy Joob
Sanitation 1 Medical Academic Center, Bangkok
Thailand
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/tcmj.tcmj_48_17

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How to cite this article:
Joob B, Wiwanitkit V. Leptin as an independent marker of metabolic syndrome. Tzu Chi Med J 2017;29:237

How to cite this URL:
Joob B, Wiwanitkit V. Leptin as an independent marker of metabolic syndrome. Tzu Chi Med J [serial online] 2017 [cited 2021 Apr 17];29:237. Available from: https://www.tcmjmed.com/text.asp?2017/29/4/237/219754

Dear Editor,

The publication on “Leptin as an independent marker of metabolic syndrome” by Tseng et al. is very interesting [1]. Tseng et al. concluded that “Serum leptin is positively correlated with MetS. It serves as an independent marker of MetS in elderly patients with T2DM [1].” In fact, the usefulness of serum leptin is widely mentioned. Nevertheless, there are many possible confounding factors that might disturb the determination. First, exercise can result in lowering leptin level [2]. Second, in the case with underlying liver problem and abnormal elevated bilirubin level (such as in cases with chronic hepatitis), the interference on leptin level measurement is possible [3]. Hence, the patients with underlying hepatitis should be excluded from the study. These factors have to be concerned in the study by Tseng et al. [1].

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Conflicts of interest

There are no conflicts of interest.

 
  References Top

1.
Tseng PW, Wu DA, Hou JS, Hsu BG. Leptin is an independent marker of metabolic syndrome in elderly adults with type 2 diabetes. Tzu Chi Med J 2017;29:109-14.  Back to cited text no. 1
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2.
Pop D, Dadârlat A, Bodizs G, Stanca L, Zdrenghea D. The response of circulating leptin levels to exercise stress testing in subjects diagnosed with metabolic syndrome. ISRN Endocrinol 2014;2014:689260.  Back to cited text no. 2
    
3.
Theriault A, Agdinaoay T, Ladao NB, Chang H, Grandinetti A. Clinical evaluation of a new non-isotopic leptin immunoassay. Clin Lab Sci 2001;14:6-8.  Back to cited text no. 3
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