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 Table of Contents  
Year : 2017  |  Volume : 29  |  Issue : 4  |  Page : 237

Leptin as an independent marker of metabolic syndrome

1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Tropical Medicine, Hainan Medical University, Hainan Sheng, China

Date of Web Publication4-Dec-2017

Correspondence Address:
Beuy Joob
Sanitation 1 Medical Academic Center, Bangkok
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tcmj.tcmj_48_17

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How to cite this article:
Joob B, Wiwanitkit V. Leptin as an independent marker of metabolic syndrome. Tzu Chi Med J 2017;29:237

How to cite this URL:
Joob B, Wiwanitkit V. Leptin as an independent marker of metabolic syndrome. Tzu Chi Med J [serial online] 2017 [cited 2021 May 7];29:237. Available from: https://www.tcmjmed.com/text.asp?2017/29/4/237/219754

Dear Editor,

The publication on “Leptin as an independent marker of metabolic syndrome” by Tseng et al. is very interesting [1]. Tseng et al. concluded that “Serum leptin is positively correlated with MetS. It serves as an independent marker of MetS in elderly patients with T2DM [1].” In fact, the usefulness of serum leptin is widely mentioned. Nevertheless, there are many possible confounding factors that might disturb the determination. First, exercise can result in lowering leptin level [2]. Second, in the case with underlying liver problem and abnormal elevated bilirubin level (such as in cases with chronic hepatitis), the interference on leptin level measurement is possible [3]. Hence, the patients with underlying hepatitis should be excluded from the study. These factors have to be concerned in the study by Tseng et al. [1].

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  References Top

Tseng PW, Wu DA, Hou JS, Hsu BG. Leptin is an independent marker of metabolic syndrome in elderly adults with type 2 diabetes. Tzu Chi Med J 2017;29:109-14.  Back to cited text no. 1
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Pop D, Dadârlat A, Bodizs G, Stanca L, Zdrenghea D. The response of circulating leptin levels to exercise stress testing in subjects diagnosed with metabolic syndrome. ISRN Endocrinol 2014;2014:689260.  Back to cited text no. 2
Theriault A, Agdinaoay T, Ladao NB, Chang H, Grandinetti A. Clinical evaluation of a new non-isotopic leptin immunoassay. Clin Lab Sci 2001;14:6-8.  Back to cited text no. 3

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