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| LETTER TO THE EDITOR |
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| Year : 2017 | Volume
: 29
| Issue : 4 | Page : 237 |
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Leptin as an independent marker of metabolic syndrome
Beuy Joob1, Viroj Wiwanitkit2
1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Tropical Medicine, Hainan Medical University, Hainan Sheng, China
| Date of Web Publication | 4-Dec-2017 |
Correspondence Address:
Beuy Joob
Sanitation 1 Medical Academic Center, Bangkok
Thailand
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/tcmj.tcmj_48_17
How to cite this article:
Joob B, Wiwanitkit V. Leptin as an independent marker of metabolic syndrome. Tzu Chi Med J 2017;29:237 |
Dear Editor,
The publication on “Leptin as an independent marker of metabolic syndrome” by Tseng et al. is very interesting [1]. Tseng et al. concluded that “Serum leptin is positively correlated with MetS. It serves as an independent marker of MetS in elderly patients with T2DM [1].” In fact, the usefulness of serum leptin is widely mentioned. Nevertheless, there are many possible confounding factors that might disturb the determination. First, exercise can result in lowering leptin level [2]. Second, in the case with underlying liver problem and abnormal elevated bilirubin level (such as in cases with chronic hepatitis), the interference on leptin level measurement is possible [3]. Hence, the patients with underlying hepatitis should be excluded from the study. These factors have to be concerned in the study by Tseng et al. [1].
Financial Support and Sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
| References | |  |
| 1. | Tseng PW, Wu DA, Hou JS, Hsu BG. Leptin is an independent marker of metabolic syndrome in elderly adults with type 2 diabetes. Tzu Chi Med J 2017;29:109-14.  [ PUBMED] [Full text] |
| 2. | Pop D, Dadârlat A, Bodizs G, Stanca L, Zdrenghea D. The response of circulating leptin levels to exercise stress testing in subjects diagnosed with metabolic syndrome. ISRN Endocrinol 2014;2014:689260. |
| 3. | Theriault A, Agdinaoay T, Ladao NB, Chang H, Grandinetti A. Clinical evaluation of a new non-isotopic leptin immunoassay. Clin Lab Sci 2001;14:6-8. [ PUBMED] |
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