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  Indian J Med Microbiol
 

Figure 1: (a) The DNA sequence of C*15:29 is identical to C*15:02:01:01 in exons 1, 2, 3, 4, 5 and 6 except for residue 420 (exon 3; codon 116; underlined) and residue 1034 (exon 6; coden 321; underlined) where A and G of C*15:02:01:01 is substituted by C and A in C*15:29 respectively (only exons 2, 3 and 6 are shown here). (b) The nucleotide substitutions introduce two amino acid replacements at residues 116 and 321 where leucine (L) and cysteine (C) of C*15:02:01:01 are replaced by a phenylalanine (F) and a tyrosine (Y) (shaded) in C*15:29 respectively. Dashes indicate nucleotide or amino acid identity with C*15:02:01:01

Figure 1: (a) The DNA sequence of C*15:29 is identical to C*15:02:01:01 in exons 1, 2, 3, 4, 5 and 6 except for residue 420 (exon 3; codon 116; underlined) and residue 1034 (exon 6; coden 321; underlined) where A and G of C*15:02:01:01 is substituted by C and A in C*15:29 respectively (only exons 2, 3 and 6 are shown here). (b) The nucleotide substitutions introduce two amino acid replacements at residues 116 and 321 where leucine (L) and cysteine (C) of C*15:02:01:01 are replaced by a phenylalanine (F) and a tyrosine (Y) (shaded) in C*15:29 respectively. Dashes indicate nucleotide or amino acid identity with C*15:02:01:01