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  Indian J Med Microbiol
 

Figure 5: Effects of LK3 on carrageenan-evoked paw thermal hyperalgesia and paw edema. LK3 (5–20 mg/kg, intraperitoneal) was administered 30 min before carrageenan injection. Then, the paw edema was assessed in the carrageenan-injected hind paws of rats at specific time (a). LK3 or vehicle (saline) was injected at 135 min after carrageenan injection and the paw withdrawal latency was measured at specific time points (b). Data was expressed as mean ± standard error of the mean, *P<0.05, **P<0.01, ***P<0.001 versus carrageenan-injected group (n = 5)

Figure 5: Effects of LK3 on carrageenan-evoked paw thermal hyperalgesia and paw edema. LK3 (5–20 mg/kg, intraperitoneal) was administered 30 min before carrageenan injection. Then, the paw edema was assessed in the carrageenan-injected hind paws of rats at specific time (a). LK3 or vehicle (saline) was injected at 135 min after carrageenan injection and the paw withdrawal latency was measured at specific time points (b). Data was expressed as mean ± standard error of the mean, *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001 versus carrageenan-injected group (<i>n</i> = 5)