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LETTER TO THE EDITOR
Ahead of print publication  

Dengue fever with chikungunya concurrent infection


1 TWS Medical Center, Bangkok, Thailand
2 Department of Community Medicine, Dr. D. Y. Patil University, Pune, Maharashtra, India; Department of Medical Science, Faculty of Medicine, University of Nis, Nis, Serbia; Department of Tropical Medicine, Hainan Medical University, Haikou, China; Department of Biological Science, Joseph Ayo Babalola University, Ilara-Mokin, Nigeria

Date of Web Publication13-Aug-2018

Correspondence Address:
Pathum Sookaromdee,
TWS Medical Center, Bangkok 10730
Thailand
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tcmj.tcmj_121_18



How to cite this URL:
Sookaromdee P, Wiwanitkit V. Dengue fever with chikungunya concurrent infection. Tzu Chi Med J [Epub ahead of print] [cited 2018 Dec 14]. Available from: http://www.tcmjmed.com/preprintarticle.asp?id=238973

Dear Editor,

We read the publication on “Clinical profile of dengue fever and coinfection with chikungunya” with a great interest [1]. Singh et al. concluded that “joint-related symptoms (pain and restricted movements) were statistically significant in chikungunya monoinfection [1]” and “there was no significant added severity of clinical features and blood investigations in patients with coinfection with dengue and chikungunya compared to those with monoinfections [1].” In fact, both dengue and chikungunya infections are common tropical mosquito-borne infections. The clinical spectrums of the two diseases are overlapping, and the diagnosis is sometimes difficult [2]. The concurrent infection is not uncommon. Nevertheless, in the presented report, Singh et al. use immunodiagnosis for diagnosis of the cases. The possibility of cross-reactivity might lead to the incorrect diagnosis [2]. In addition, there is also a chance of the possible other additional concurrent infection such as Zika virus infection. According to the recent report from Thailand, the triple reactivity to all three infections, dengue, Zika, and chikungunya, in the same person is not uncommon [3].

Financial support and sponsorship

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Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Singh J, Dinkar A, Singh RG, Siddiqui MS, Sinha N, Singh SK. Clinical profile of dengue fever and coinfection with chikungunya. Tzu Chi Med J 2018;30:158-64.  Back to cited text no. 1
  [Full text]  
2.
Wiwanitkit V. Dengue fever: Diagnosis and treatment. Expert Rev Anti Infect Ther 2010;8:841-5.  Back to cited text no. 2
    
3.
Wikan N, Suputtamongkol Y, Yoksan S, Smith DR, Auewarakul P. Immunological evidence of Zika virus transmission in Thailand. Asian Pac J Trop Med 2016;9:141-4.  Back to cited text no. 3
    




 

 
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